Synthetic Biology for Chemicals and Materials

Feb 19, 2018 09:30 - 14:00 UTC-03
R. Magalhães Castro, 174 - Riachuelo, Rio de Janeiro - RJ, 20961-020, Rio de Janeiro, State of Rio de Janeiro, Brazil

The SENAI Innovation Institute for Biosynthetic and the Massachusetts Institute of Technology (MIT) invite for the Synthetic Biology for Chemicals and Materials Symposium. The meeting, which will take place on February 19, 2018 in Rio de Janeiro, will deal with the application of synthetic biology in chemistry and materials, with lectures by two leading researchers on the subject: Prof. Kristala Prather and Prof. Bradley Olsen. Registration is free, but a confirmation email must be sent to Mariana Doria:




9:30 – 10:00   Welcome Coffee

10:00 – 11:00   “Glucaric acid production in E. coli: a case study for engineering microbial synthesis”  Presented by Prof. Kristala Prather

Microbial production provides a practical alternative to chemical synthesis for a number of molecules. Extensive metabolic engineering is often required to achieve target titers, yields and productivity metrics, especially for heterologous hosts and novel products. This presentation will provide an overview of our labs efforts to engineer Escherichia coli for the production of glucaric acid, from initial pathway construction to the development of autonomous control methods for regulating metabolic flux. Key remaining challenges and opportunities for further enhancement will also be presented.

11:00 – 12:00   “Synthetic Biology and Bioconjugate Chemistry for New Materials” Presented by: Prof. Bradley Olsen

Synthetic biology enables the design and synthesis of a wide variety of different enzymes, protein polymers, and other materials that can have an important impact across the areas of human health and sustainability. This presentation will review key scientific approaches and opportunities for material production using synthetic biology, identifying key challenges in material design and synthesis. Finally, it will end with the discussion of several different case studies regarding the production of different biopolymer and biohybrid materials for the cosmetics industry.

12:00 – 13:00   Lunch

13:00 – 14:00   Discussion & Concluding Remarks

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